Effects of cannabis on the endocannabinoid system

It is an important medical discovery because it is believed to work synergistically with other cannabinoids, especially THC.

Scientists have discovered more than 100 active cannabinoid compounds produced by the cannabis plant. Cannabinoids are molecules that interact with the human body’s cannabinoid receptors. The most abundant and well-known cannabinoid compound is THC, followed closely by CBD. These compounds act very similarly to the naturally occurring endocannabinoids produced by the body to help regulate vital systems that keep us healthy. The endocannabinoid system or ECS was only discovered within the last thirty years. Research has led experts to believe that the ECS works to regulate homeostasis. It helps the body to maintain balance. Consuming cannabis in various ways introduces cannabinoids into the bloodstream and to the brain. The cannabinoids then bind to receptors that make up the ECS and create varying therapeutic effects. THC is the most famous cannabinoid and associated with psychoactive effects. The body naturally produces a neurotransmitter and endocannabinoid known as anandamide. THC and anandamide activate the same cannabinoid receptors in the human body. Cannabidiol or CBD has recently gained attention for its many therapeutic properties. While not a psychoactive compound, CBD interacts with the brain and endocannabinoid system. It is an important medical discovery because it is believed to work synergistically with other cannabinoids, especially THC. This entourage effect means that cannabinoids offer enhanced effects when they partner together. Plus, CBD is helpful in that it offsets some of the negative effects of THC. Because it doesn’t cause a high sensation, patients are able to take CBD throughout the day with no impairment. Cannabis has shown promise in treating a lengthy list of medical ailments and symptoms including migraines, insomnia, anxiety, glaucoma, nausea, cancer, Alzheimers, seizures, arthritis, PTSD, depression, addiction and more.

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